Cardiac arrest following reversal of muscle relaxation by pyridostigmine - A case report -

Anesthesia and Pain Medicine 2014³â 9±Ç 3È£ p.205 ~ p.208

Á¶ÁØ¿µ(Jo Jun-Young) - University of Ulsan College of Medicine Asan Medical Center Department of Anesthesiology and Pain Medicine
ÀÌÁ¤¹Î(Yi Jung-Min) - University of Ulsan College of Medicine Asan Medical Center Department of Anesthesiology and Pain Medicine
ÀÌÀ±°æ(Lee Yoon-Kyung) - Hallym University College of Medicine Department of Anesthesiology and Pain Medicine
±¸½Â¿ì(Ku Seung-Woo) - University of Ulsan College of Medicine Asan Medical Center Department of Anesthesiology and Pain Medicine
¹ÚÆòȯ(Park Pyung-Hwan) - University of Ulsan College of Medicine Asan Medical Center Department of Anesthesiology and Pain Medicine

Abstract

The anticholinesterase pyridostigmine is usually used as a reversal agent of non-depolarizing muscle relaxants in general anesthesia. Most adverse muscarinic effects of anticholinesterases are controlled by anticholinergics; however, there is still a potential for fatal cardiac complications. We report a case of cardiac arrest associated with coronary vasospasm that developed during emergence from general anesthesia in a 61-year-old male patient undergoing uvulopalatopharyngoplasty with preoperatively undiagnosed coronary vasospastic angina. Anticholinesterases should be administered with caution for neuromuscular blockade reversal, especially in patients with coronary vasospastic angina.

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Cardiac arrest, Coronary spasm, Pyridostigmine, Reversal of neuromuscular block
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